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Wafik S. El-Deiry

Wafik S. El-Deiry

Brown University

研究方向

自噬p53肿瘤抑制细胞死亡信号通路DNA损伤TRAIL通路缺氧药物抵抗新型疗法

联系方式

cd****@cancerdrugresist.net

个人简介

Wafik S. El-Deiry，现任Brown University。主要从事自噬、p53肿瘤抑制、细胞死亡信号通路、DNA损伤、TRAIL通路研究。

科研成果

19
论文成果

代表作品

优先展示有引用数据的代表论文。

高引文章

按引用次数从高到低排列。

1
WAF1, a potential mediator of p53 tumor suppression
Cell1993被引 8,413
2
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Cell Death and Differentiation2018被引 6,770
3
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
Cell Death and Differentiation2008被引 3,396
4
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
Cell1992被引 3,085
5
Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
New England Journal of Medicine2018被引 2,832
6
Targeting apoptosis in cancer therapy
Nature Reviews Clinical Oncology2020被引 2,668
7
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
Cell Death and Differentiation2011被引 2,444
8
WAF1/CIP₁ is induced in p53-mediated G1 arrest and apoptosis.
PubMed1994被引 2,044
9
Definition of a consensus binding site for p53
Nature Genetics1992被引 2,017
10
Overview of cell death signaling pathways
Cancer Biology & Therapy2005被引 1,321
11
Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer2021被引 772
12
Apoptotic cell death in disease—Current understanding of the NCCD 2023
Cell Death and Differentiation2023被引 376
13
Heterogeneity in Cancer
ORCID2025
14
GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer
ORCID2023
15
BRCA1/2 Reversion Mutations in Patients Treated with Poly ADP-Ribose Polymerase (PARP) Inhibitors or Platinum Agents
ORCID2022
16
Integrin/TGF-β1 Inhibitor GLPG-0187 Blocks SARS-CoV-2 Delta and Omicron Pseudovirus Infection of Airway Epithelial Cells In Vitro, Which Could Attenuate Disease Severity
ORCID2022
17
Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer
ORCID2022
18
Immunotherapy for Colorectal Cancer: Mechanisms and Predictive Biomarkers
ORCID2022
19
Differential p53-Mediated Cellular Responses to DNA-Damaging Therapeutic Agents
ORCID2021

最后更新： 2026/9/29 06:14:27